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RAAS


The renin–angiotensin system (RAS) or the renin–angiotensin–aldosterone system (RAAS) is a hormone system that is involved in the regulation of the plasma sodium concentration and arterial blood pressure.

  • Azilsartan EY1822

    Azilsartan是angiotensin II type 1 (AT1)（血管紧张素II 1型）受体拮抗剂，IC50为2.6 nM。

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  • Lisinopril EY1775

    Lisinopril dihydrate是血管紧张素转化酶抑制剂，可作用于高血压，充血性心力衰竭和心脏病等。

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  • LCZ696 EY1658

    LCZ696是首个2型血管紧张素受体（AT II）和脑啡肽酶（neprilysin）双重抑制剂，由Valsartan和NEP抑制剂前提药物AHU377(1:1)组成。

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  • Irbesartan EY1584

    Irbesartan 是1型血管紧张素II（AT1）受体拮抗剂，IC50为1.3 nM。

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  • Aliskiren Hemifumarate EY1077

    Aliskiren hemifumarate是肾素的直接抑制剂，IC50为1.5 nM。

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